A Functional Variant of the Dimethylarginine Dimethylaminohydrolase-2 Gene Is Associated with Insulin Sensitivity

BACKGROUND: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide synthase, which was associated with insulin resistance. Dimethylarginine dimethylaminohydrolase (DDAH) is the major determinant of plasma ADMA. Examining data from the DIAGRAM+ (Diabetes Genetics Re...

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Hlavní autoři: Andreozzi, Francesco, Presta, Ivan, Mannino, Gaia Chiara, Scarpelli, Daniela, Di Silvestre, Sara, Di Pietro, Natalia, Succurro, Elena, Sciacqua, Angela, Pandolfi, Assunta, Consoli, Agostino, Hribal, Marta Letizia, Perticone, Francesco, Sesti, Giorgio
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338696/
https://ncbi.nlm.nih.gov/pubmed/22558392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036224
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