A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients

BACKGROUND: Myocardial infarction is the main mortality cause in patients with type 2 diabetes (T2DM). Endothelial dysfunction due to reduced bioavailability of nitric oxide (NO) is an early step of atherogenesis. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of NO synthesis, and it...

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書誌詳細
出版年:Cardiovasc Diabetol
主要な著者: Mannino, Gaia Chiara, Pezzilli, Serena, Averta, Carolina, Fuoco, Anastasia, Spiga, Rosangela, Mancuso, Elettra, Di Fatta, Concetta, Perticone, Francesco, Prudente, Sabrina, Trischitta, Vincenzo, Andreozzi, Francesco, Sesti, Giorgio
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
Original Investigation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693196/
https://ncbi.nlm.nih.gov/pubmed/31409409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-019-0906-1
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