A Functional Variant of the Dimethylarginine Dimethylaminohydrolase-2 Gene Is Associated with Insulin Sensitivity

BACKGROUND: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide synthase, which was associated with insulin resistance. Dimethylarginine dimethylaminohydrolase (DDAH) is the major determinant of plasma ADMA. Examining data from the DIAGRAM+ (Diabetes Genetics Re...

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Detalhes bibliográficos
Main Authors: Andreozzi, Francesco, Presta, Ivan, Mannino, Gaia Chiara, Scarpelli, Daniela, Di Silvestre, Sara, Di Pietro, Natalia, Succurro, Elena, Sciacqua, Angela, Pandolfi, Assunta, Consoli, Agostino, Hribal, Marta Letizia, Perticone, Francesco, Sesti, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338696/
https://ncbi.nlm.nih.gov/pubmed/22558392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036224
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