A Functional Variant of the Dimethylarginine Dimethylaminohydrolase-2 Gene Is Associated with Insulin Sensitivity

BACKGROUND: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide synthase, which was associated with insulin resistance. Dimethylarginine dimethylaminohydrolase (DDAH) is the major determinant of plasma ADMA. Examining data from the DIAGRAM+ (Diabetes Genetics Re...

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Bibliografiske detaljer
Main Authors: Andreozzi, Francesco, Presta, Ivan, Mannino, Gaia Chiara, Scarpelli, Daniela, Di Silvestre, Sara, Di Pietro, Natalia, Succurro, Elena, Sciacqua, Angela, Pandolfi, Assunta, Consoli, Agostino, Hribal, Marta Letizia, Perticone, Francesco, Sesti, Giorgio
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338696/
https://ncbi.nlm.nih.gov/pubmed/22558392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036224
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