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In Vitro RNase and Nucleic Acid Binding Activities Implicate Coilin in U snRNA Processing

Coilin is known as the marker protein for Cajal bodies (CBs), subnuclear domains important for the biogenesis of small nuclear ribonucleoproteins (snRNPs) which function in pre-mRNA splicing. CBs associate non-randomly with U1 and U2 gene loci, which produce the small nuclear RNA (snRNA) component o...

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Autors principals: Broome, Hanna J., Hebert, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338655/
https://ncbi.nlm.nih.gov/pubmed/22558428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036300
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