Mitochondrial Genome Instability and ROS Enhance Intestinal Tumorigenesis in APC(Min/+) Mice

Alterations in mitochondrial oxidative phosphorylation have long been documented in tumors. Other types of mitochondrial dysfunction, including altered reactive oxygen species (ROS) production and apoptosis, also can contribute to tumorigenesis and cancer phenotypes. Furthermore, mutation and altere...

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Bibliografski detalji
Glavni autori: Woo, Dong Kyun, Green, Paula D., Santos, Janine H., D'Souza, Anthony D., Walther, Zenta, Martin, W. David, Christian, Brooke E., Chandel, Navdeep S., Shadel, Gerald S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2012
Teme:
Short Communication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338350/
https://ncbi.nlm.nih.gov/pubmed/22056359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.10.003
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