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Mitochondrial Genome Instability and ROS Enhance Intestinal Tumorigenesis in APC(Min/+) Mice
Alterations in mitochondrial oxidative phosphorylation have long been documented in tumors. Other types of mitochondrial dysfunction, including altered reactive oxygen species (ROS) production and apoptosis, also can contribute to tumorigenesis and cancer phenotypes. Furthermore, mutation and altere...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Investigative Pathology
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338350/ https://ncbi.nlm.nih.gov/pubmed/22056359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.10.003 |
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