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Eculizumab for Dense Deposit Disease and C3 Glomerulonephritis
BACKGROUND AND OBJECTIVES: The principle defect in dense deposit disease and C3 glomerulonephritis is hyperactivity of the alternative complement pathway. Eculizumab, a monoclonal antibody that binds to C5 to prevent formation of the membrane attack complex, may prove beneficial. DESIGN, SETTING, PA...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338285/ https://ncbi.nlm.nih.gov/pubmed/22403278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.12901211 |
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