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Secretory Pathway Stress Responses as Possible Mechanisms of Disease Involving Golgi Ca(2+) Pump Dysfunction
In mammalian tissues, uptake of Ca(2+) and Mn(2+) by Golgi membranes is mediated by the secretory pathway Ca(2+)- ATPases, SPCA1 and SPCA2, encoded by the ATP2C1 and ATP2C2 genes. Loss of one copy of the ATP2C1 gene, which causes SPCA1 haploinsufficiency, leads to squamous cell tumors of keratinized...
Bewaard in:
| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338190/ https://ncbi.nlm.nih.gov/pubmed/21674634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biof.141 |
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