Decreased extra-renal urate excretion is a common cause of hyperuricemia

ABCG2, also known as BCRP, is a high-capacity urate exporter, the dysfunction of which raises gout/hyperuricemia risk. Generally, hyperuricemia has been classified into urate 'overproduction type' and/or 'underexcretion type' based solely on renal urate excretion, without conside...

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Main Authors: Ichida, Kimiyoshi, Matsuo, Hirotaka, Takada, Tappei, Nakayama, Akiyoshi, Murakami, Keizo, Shimizu, Toru, Yamanashi, Yoshihide, Kasuga, Hiroshi, Nakashima, Hiroshi, Nakamura, Takahiro, Takada, Yuzo, Kawamura, Yusuke, Inoue, Hiroki, Okada, Chisa, Utsumi, Yoshitaka, Ikebuchi, Yuki, Ito, Kousei, Nakamura, Makiko, Shinohara, Yoshihiko, Hosoyamada, Makoto, Sakurai, Yutaka, Shinomiya, Nariyoshi, Hosoya, Tatsuo, Suzuki, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337984/
https://ncbi.nlm.nih.gov/pubmed/22473008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1756
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