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The binding site and mechanism of the RNA polymerase inhibitor tagetitoxin: An issue open to debate
In a recent paper in the Journal of Biological Chemistry, Artsimovitch et al.(2) report a major revision of a crystallographic model and proposed mechanism of the RNA polymerase inhibitor, tagetitoxin. This reassessment is based on theoretical modeling using molecular dynamics simulations. Here, we...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337825/ https://ncbi.nlm.nih.gov/pubmed/22414754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.19468 |
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