Role of Coupled-Dynamics in the Catalytic Activity of Prokaryotic-like Prolyl-tRNA Synthetases

Prolyl-tRNA synthetases (ProRSs) have been shown to activate both cognate and some noncognate amino acids and attach them to specific tRNA(Pro) substrates. For example, alanine, which is smaller than cognate proline, is misactivated by Escherichia coli ProRS. Mischarged Ala-tRNA(Pro) is hydrolyzed b...

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Detaylı Bibliyografya
Asıl Yazarlar: Sanford, Brianne, Cao, Bach, Johnson, James M., Zimmerman, Kurt, Strom, Alexander M., Mueller, Robyn M., Bhattacharyya, Sudeep, Musier-Forsyth, Karin, Hati, Sanchita
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337710/
https://ncbi.nlm.nih.gov/pubmed/22356126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300097g
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