Direct Observation of Cooperative Protein Structural Dynamics of Homodimeric Hemoglobin from 100 ps to 10 ms with Pump–Probe X-ray Solution Scattering

[Image: see text] Proteins serve as molecular machines in performing their biological functions, but the detailed structural transitions are difficult to observe in their native aqueous environments in real time. For example, despite extensive studies, the solution-phase structures of the intermedia...

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Main Authors: Kim, Kyung Hwan, Muniyappan, Srinivasan, Oang, Key Young, Kim, Jong Goo, Nozawa, Shunsuke, Sato, Tokushi, Koshihara, Shin-ya, Henning, Robert, Kosheleva, Irina, Ki, Hosung, Kim, Youngmin, Kim, Tae Wu, Kim, Jeongho, Adachi, Shin-ichi, Ihee, Hyotcherl
Format: Artigo
Language:Inglês
Published: American Chemical Society 2012
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337689/
https://ncbi.nlm.nih.gov/pubmed/22494177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210856v
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