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Cooperative protein structural dynamics of homodimeric hemoglobin linked to water cluster at subunit interface revealed by time-resolved X-ray solution scattering

Homodimeric hemoglobin (HbI) consisting of two subunits is a good model system for investigating the allosteric structural transition as it exhibits cooperativity in ligand binding. In this work, as an effort to extend our previous study on wild-type and F97Y mutant HbI, we investigate structural dy...

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Détails bibliographiques
Publié dans:Struct Dyn
Auteurs principaux: Kim, Jong Goo, Muniyappan, Srinivasan, Oang, Key Young, Kim, Tae Wu, Yang, Cheolhee, Kim, Kyung Hwan, Kim, Jeongho, Ihee, Hyotcherl
Format: Artigo
Langue:Inglês
Publié: American Crystallographic Association 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833754/
https://ncbi.nlm.nih.gov/pubmed/27158635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4947071
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