Immunogenicity and Protective Efficacy of a Novel Recombinant BCG Strain Overexpressing Antigens Ag85A and Ag85B

Recombinant Bacillus Calmette-Guérin (rBCG) strain is the promising vaccine candidate for tuberculosis (TB) prevention, which aims at providing more enduring and enhanced protection than the parental BCG vaccine. In this study, three rBCG strains overexpressing immunodominant antigens Ag85B (rBCG::8...

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Autores principales: Wang, Chun, Fu, Ruiling, Chen, Zhenhua, Tan, Kun, Chen, Lingxia, Teng, Xindong, Lu, Jia, Shi, Chunwei, Fan, Xionglin
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337592/
https://ncbi.nlm.nih.gov/pubmed/22570667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/563838
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