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Overexpression of a Mycobacterium ulcerans Ag85B-EsxH Fusion Protein in Recombinant BCG Improves Experimental Buruli Ulcer Vaccine Efficacy

Buruli ulcer (BU) vaccine design faces similar challenges to those observed during development of prophylactic tuberculosis treatments. Multiple BU vaccine candidates, based upon Mycobacterium bovis BCG, altered Mycobacterium ulcerans (MU) cells, recombinant MU DNA, or MU protein prime-boosts, have...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: Hart, Bryan E., Lee, Sunhee
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179062/
https://ncbi.nlm.nih.gov/pubmed/27941982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005229
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