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Overexpression of a Mycobacterium ulcerans Ag85B-EsxH Fusion Protein in Recombinant BCG Improves Experimental Buruli Ulcer Vaccine Efficacy

Buruli ulcer (BU) vaccine design faces similar challenges to those observed during development of prophylactic tuberculosis treatments. Multiple BU vaccine candidates, based upon Mycobacterium bovis BCG, altered Mycobacterium ulcerans (MU) cells, recombinant MU DNA, or MU protein prime-boosts, have...

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Bibliografische gegevens
Gepubliceerd in:PLoS Negl Trop Dis
Hoofdauteurs: Hart, Bryan E., Lee, Sunhee
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179062/
https://ncbi.nlm.nih.gov/pubmed/27941982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005229
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