Mutant p53 cooperates with ETS2 to promote etoposide resistance

Mutant p53 (mtp53) promotes chemotherapy resistance through multiple mechanisms, including disabling proapoptotic proteins and regulating gene expression. Comparison of genome wide analysis of mtp53 binding revealed that the ETS-binding site motif (EBS) is prevalent within predicted mtp53-binding si...

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Detalhes bibliográficos
Main Authors: Do, Phi M., Varanasi, Lakshman, Fan, Songqing, Li, Chunyang, Kubacka, Iwona, Newman, Virginia, Chauhan, Krishna, Daniels, Silvano Rakeem, Boccetta, Maurizio, Garrett, Michael R., Li, Runzhao, Martinez, Luis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337457/
https://ncbi.nlm.nih.gov/pubmed/22508727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.181685.111
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