Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome comprising familial/genetic HLH (FHL) and secondary HLH. In the HLH-94 study, with an estimated 5-year probability of survival (pSu) of 54% (95% confidence interval, 48%-60%), systemic therapy included etoposid...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Bergsten, Elisabet, Horne, AnnaCarin, Aricó, Maurizio, Astigarraga, Itziar, Egeler, R. Maarten, Filipovich, Alexandra H., Ishii, Eiichi, Janka, Gritta, Ladisch, Stephan, Lehmberg, Kai, McClain, Kenneth L., Minkov, Milen, Montgomery, Scott, Nanduri, Vasanta, Rosso, Diego, Henter, Jan-Inge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785801/
https://ncbi.nlm.nih.gov/pubmed/28935695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-788349
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