Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation in TF binding and gene expression is challenging due to environmental differences between individuals and cell types. To address this proble...

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Autori principali: Reddy, Timothy E., Gertz, Jason, Pauli, Florencia, Kucera, Katerina S., Varley, Katherine E., Newberry, Kimberly M., Marinov, Georgi K., Mortazavi, Ali, Williams, Brian A., Song, Lingyun, Crawford, Gregory E., Wold, Barbara, Willard, Huntington F., Myers, Richard M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337432/
https://ncbi.nlm.nih.gov/pubmed/22300769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.131201.111
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