Caricamento...

Actinomycin D induced DNase I hypersensitivity and asymmetric structure transmission in a DNA hexadecamer.

DNase I cleavage rates and nmr chemical shifts are shown to change for DNA sequences distal to an intercalated actinomycin D molecule in a duplex hexadecamer upon drug binding. Both sets of observations suggest that the source of these changes is a DNA-mediated structural response. The nmr results i...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Bishop, K D, Borer, P N, Huang, Y Q, Lane, M J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC333724/
https://ncbi.nlm.nih.gov/pubmed/2017369
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !