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Actinomycin D induced DNase I hypersensitivity and asymmetric structure transmission in a DNA hexadecamer.
DNase I cleavage rates and nmr chemical shifts are shown to change for DNA sequences distal to an intercalated actinomycin D molecule in a duplex hexadecamer upon drug binding. Both sets of observations suggest that the source of these changes is a DNA-mediated structural response. The nmr results i...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1991
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333724/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2017369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.4.871 |
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