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Mouse Models of Spinocerebellar Ataxia Type 3 (Machado-Joseph Disease)
Machado-Joseph disease, also called spinocerebellar ataxia type 3 (MJD/SCA3), is a hereditary and neurodegenerative movement disorder caused by ataxin-3 with a pathological polyglutamine stretch (mutant ataxin-3). Seven transgenic mouse models expressing full-length human mutant ataxin-3 throughout...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337014/ https://ncbi.nlm.nih.gov/pubmed/22451301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-012-0117-x |
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