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Cooperation between Rb and Arf in suppressing mouse retinoblastoma
Retinoblastoma is a pediatric cancer that has served as a paradigm for tumor suppressor gene function. Retinoblastoma is initiated by RB gene mutations, but the subsequent cooperating mutational events leading to tumorigenesis are poorly characterized. We investigated what these additional genomic a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336990/ https://ncbi.nlm.nih.gov/pubmed/22484813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61403 |
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