Učitavanje...
MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice
Tregs expressing the transcription factor Foxp3 suppress self-reactive T cells, prevent autoimmunity, and help contain immune responses to foreign antigens, thereby limiting the potential for inadvertent tissue damage. Mutations in the FOXP3 gene result in Treg deficiency in mice and humans, which l...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336968/ https://ncbi.nlm.nih.gov/pubmed/22466646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40591 |
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