Chargement en cours...
Ligand-Specific Roles for Transmembrane 5 Serine Residues in the Binding and Efficacy of Dopamine D(1) Receptor Catechol Agonists
To refine further the structure-activity relationships of D(1) dopamine receptor agonists, we investigated the roles of three conserved serine residues [Ser198(5.42), Ser199(5.43), and Ser202(5.46)] in agonist binding and receptor activation. These transmembrane domain 5 (TM5) residues are believed...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336807/ https://ncbi.nlm.nih.gov/pubmed/22334593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.077339 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|