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Analogues of doxanthrine reveal differences between the dopamine D(1) receptor binding properties of chromanoisoquinolines and hexahydrobenzo[a]phenanthridines
Efforts to develop selective agonists for dopamine D(1)-like receptors led to the discovery of dihydrexidine and doxanthrine, two bioisosteric β-phenyldopamine-type full agonist ligands that display selectivity and potency at D(1)-like receptors. We report herein an improved methodology for the synt...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264828/ https://ncbi.nlm.nih.gov/pubmed/22204903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.11.039 |
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