Interindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass Spectrometry

Multidrug-associated protein 2 (MRP2) is an efflux transporter that is expressed at the bile canalicular membrane. To allow in vitro to in vivo extrapolation of the contribution of MRP2 toward hepatic disposition of its substrates, data on the interindividual variability of hepatic MRP2 protein expr...

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Autores principales: Deo, Anand K., Prasad, Bhagwat, Balogh, Larissa, Lai, Yurong, Unadkat, Jashvant D.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2012
Materias:
Short Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336801/
https://ncbi.nlm.nih.gov/pubmed/22318656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.043810
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