Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

Mitochondria exist in dynamic networks that undergo fusion and fission. Mitochondrial fusion and fission are mediated by several GTPases in the outer mitochondrial membrane, notably mitofusin-2 (Mfn-2), which promotes fusion, and dynamin-related protein (Drp-1), which promotes fission. We report tha...

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Main Authors: Rehman, Jalees, Zhang, Hannah J., Toth, Peter T., Zhang, Yanmin, Marsboom, Glenn, Hong, Zhigang, Salgia, Ravi, Husain, Aliya N., Wietholt, Christian, Archer, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2012
Assuntos:
Research Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336787/
https://ncbi.nlm.nih.gov/pubmed/22321727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-196543
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