Controlling murine and rat chronic pain through A(3) adenosine receptor activation

Clinical management of chronic neuropathic pain is limited by marginal effectiveness and unacceptable side effects of current drugs. We demonstrate A(3) adenosine receptor (A(3)AR) agonism as a new target-based therapeutic strategy. The development of mechanoallodynia in a well-characterized mouse m...

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Bibliographic Details
Main Authors: Chen, Zhoumou, Janes, Kali, Chen, Collin, Doyle, Tim, Bryant, Leesa, Tosh, Dilip K., Jacobson, Kenneth A., Salvemini, Daniela
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2012
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336784/
https://ncbi.nlm.nih.gov/pubmed/22345405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-201541
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