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Sequence-dependent contribution of distal binding domains to CAP protein-DNA binding affinity.

We report measurements of the relative binding affinity of CAP for DNA sequences which have been systematically mutated in the region flanking the consensus binding site. Our experiments focus on the locus one helical turn from the dyad axis where DNA bending toward the minor groove is induced upon...

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Detalhes bibliográficos
Main Authors: Dalma-Weiszhausz, D D, Gartenberg, M R, Crothers, D M
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC333656/
https://ncbi.nlm.nih.gov/pubmed/1849264
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