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Common and Variable Contributions of Fis Residues to High-Affinity Binding at Different DNA Sequences
Fis is a nucleoid-associated protein that interacts with poorly related DNA sequences with a high degree of specificity. A difference of more than 3 orders of magnitude in apparent K(d) values was observed between specific (K(d), ∼1 to 4 nM) and nonspecific (K(d), ∼4 μM) DNA binding. To examine the...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1428148/ https://ncbi.nlm.nih.gov/pubmed/16513738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.6.2081-2095.2006 |
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