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Inhibiting homologous recombination for cancer therapy
We review the rationale for seeking inhibitors of homologous recombination (HR) repair for use in cancer therapy. Cells use HR as one way to repair DNA double-strand breaks that arise directly from treatments such as radiotherapy, or indirectly during replication when forks encounter other damage. H...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336066/ https://ncbi.nlm.nih.gov/pubmed/22336907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.13.2.18872 |
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