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Interleukin-1 or phorbol induction of the stromelysin promoter requires an element that cooperates with AP-1.

Interleukin-1, a mediator of inflammation, or tumor promoting phorbol esters induce transcription of stromelysin, a metalloproteinase that degrades extracellular matrix molecules and that is overexpressed in diseases such as rheumatoid arthritis. Sequences required for induction of transcription of...

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Pubblicato in:Nucleic Acids Res
Autori principali: Sirum-Connolly, K, Brinckerhoff, C E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1991
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333599/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1901643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.2.335
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