Interleukin-1 or phorbol induction of the stromelysin promoter requires an element that cooperates with AP-1.
Interleukin-1, a mediator of inflammation, or tumor promoting phorbol esters induce transcription of stromelysin, a metalloproteinase that degrades extracellular matrix molecules and that is overexpressed in diseases such as rheumatoid arthritis. Sequences required for induction of transcription of...
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| Udgivet i: | Nucleic Acids Res |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1991
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1901643/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.2.335 |
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