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Interleukin-1 or phorbol induction of the stromelysin promoter requires an element that cooperates with AP-1.
Interleukin-1, a mediator of inflammation, or tumor promoting phorbol esters induce transcription of stromelysin, a metalloproteinase that degrades extracellular matrix molecules and that is overexpressed in diseases such as rheumatoid arthritis. Sequences required for induction of transcription of...
Uloženo v:
| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1991
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC333599/ https://ncbi.nlm.nih.gov/pubmed/1901643 |
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