CHRONIC DIRECT RENIN INHIBITION WITH ALISKIREN PREVENTS THE DEVELOPMENT OF HYPERTENSION IN CYP1A1-REN2 TRANSGENIC RATS WITH INDUCIBLE ANG II-DEPENDENT HYPERTENSION

INTRODUCTION: The present study was performed to determine if chronic direct renin inhibition can prevent the development of slowly progressive ANG II-dependent hypertension and the associated derangements in renal function in Cyp1a1-Ren2 transgenic rats with inducible expression of the Ren2 gene. M...

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Hlavní autoři: Huang, Lily, Howard, Catherine G., Mitchell, Kenneth D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335984/
https://ncbi.nlm.nih.gov/pubmed/22261625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAJ.0b013e3182410d1e
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