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Renal functional responses to selective intrarenal renin inhibition in Cyp1a1-Ren2 transgenic rats with ANG II-dependent malignant hypertension

Angiotensin (ANG) II-dependent hypertension is characterized by increases in intrarenal ANG II levels, derangement in renal hemodynamics, and augmented tubular sodium reabsorptive capability. Increased nephron expression of renin-angiotensin system components, such as angiotensinogen by proximal tub...

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Detalhes bibliográficos
Main Authors: Howard, Catherine G., Mitchell, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251336/
https://ncbi.nlm.nih.gov/pubmed/21993885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00187.2011
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