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The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer
The deubiquitinating enzyme USP2a has shown oncogenic properties in many cancer types by impairing ubiquitination of FASN, MDM2, MDMX or Aurora A. Aberrant expression of USP2a has been linked to progression of human tumors, particularly prostate cancer. However, little is known about the role of USP...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335918/ https://ncbi.nlm.nih.gov/pubmed/22370483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.6.19550 |
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