Differential Modulation of Retinal Degeneration by Ccl2 and Cx3cr1 Chemokine Signalling

Microglia and macrophages are recruited to sites of retinal degeneration where local cytokines and chemokines determine protective or neurotoxic microglia responses. Defining the role of Ccl2-Ccr2 and Cx3cl1-Cx3cr1 signalling for retinal pathology is of particular interest because of its potential r...

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Autors principals: Luhmann, Ulrich F. O., Lange, Clemens A., Robbie, Scott, Munro, Peter M. G., Cowing, Jill A., Armer, Hannah E. J., Luong, Vy, Carvalho, Livia S., MacLaren, Robert E., Fitzke, Frederick W., Bainbridge, James W. B., Ali, Robin R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335860/
https://ncbi.nlm.nih.gov/pubmed/22545116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035551
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