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Heme Oxygenase Isoforms Differ in Their Subcellular Trafficking during Hypoxia and Are Differentially Modulated by Cytochrome P450 Reductase

Heme oxygenase (HO) degrades heme in concert with NADPH cytochrome P450 reductase (CPR) which donates electrons to the reaction. Earlier studies reveal the importance of the hydrophobic carboxy-terminus of HO-1 for anchorage to the endoplasmic reticulum (ER) which facilitates the interaction with CP...

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Detalhes bibliográficos
Main Authors: Linnenbaum, Monika, Busker, Mareike, Kraehling, Jan R., Behrends, Soenke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335857/
https://ncbi.nlm.nih.gov/pubmed/22545110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035483
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