Etiopathogenesis of Insulin Autoimmunity

Autoimmunity against pancreatic islet beta cells is strongly associated with proinsulin, insulin, or both. The insulin autoreactivity is particularly pronounced in children with young age at onset of type 1 diabetes. Possible mechanisms for (pro)insulin autoimmunity may involve beta-cell destruction...

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Autores principales: Kanatsuna, Norio, Papadopoulos, George K., Moustakas, Antonis K., Lenmark, Åke
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335545/
https://ncbi.nlm.nih.gov/pubmed/22567309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/457546
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