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The type I interferon system in the etiopathogenesis of autoimmune diseases

Many patients with systemic autoimmune diseases have signs of a continuous production of type I interferon (IFN) and display an increased expression of IFN-α-regulated genes. The reason for the on-going IFN-α synthesis in these patients seems to be an activation of plasmacytoid dendritic cells (pDCs...

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Autor principal: Rönnblom, Lars
Format: Artigo
Idioma:Inglês
Publicat: Informa Healthcare 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207297/
https://ncbi.nlm.nih.gov/pubmed/22066971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03009734.2011.624649
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