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Dynamic Interaction of cBid with Detergents, Liposomes and Mitochondria
The BH3-only protein Bid plays a key role in the induction of mitochondrial apoptosis, but its mechanism of action is still not completely understood. Here we studied the two main activation events of Bid: Caspase-8 cleavage and interaction with the membrane bilayer. We found a striking reversible b...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335097/ https://ncbi.nlm.nih.gov/pubmed/22540011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035910 |
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