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DW-MRI as a Biomarker to Compare Therapeutic Outcomes in Radiotherapy Regimens Incorporating Temozolomide or Gemcitabine in Glioblastoma

The effectiveness of the radiosensitizer gemcitabine (GEM) was evaluated in a mouse glioma along with the imaging biomarker diffusion-weighted magnetic resonance imaging (DW-MRI) for early detection of treatment effects. A genetically engineered murine GBM model [Ink4a-Arf(−/−) Pten(loxP/loxP)/Ntv-a...

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Detalles Bibliográficos
Autores principales: Galbán, Stefanie, Lemasson, Benjamin, Williams, Terence M., Li, Fei, Heist, Kevin A., Johnson, Timothy D., Leopold, Judith S., Chenevert, Thomas L., Lawrence, Theodore S., Rehemtulla, Alnawaz, Mikkelsen, Tom, Holland, Eric C., Galbán, Craig J., Ross, Brian D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334987/
https://ncbi.nlm.nih.gov/pubmed/22536446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035857
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