DW-MRI as a Biomarker to Compare Therapeutic Outcomes in Radiotherapy Regimens Incorporating Temozolomide or Gemcitabine in Glioblastoma

The effectiveness of the radiosensitizer gemcitabine (GEM) was evaluated in a mouse glioma along with the imaging biomarker diffusion-weighted magnetic resonance imaging (DW-MRI) for early detection of treatment effects. A genetically engineered murine GBM model [Ink4a-Arf(−/−) Pten(loxP/loxP)/Ntv-a...

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Detalhes bibliográficos
Main Authors: Galbán, Stefanie, Lemasson, Benjamin, Williams, Terence M., Li, Fei, Heist, Kevin A., Johnson, Timothy D., Leopold, Judith S., Chenevert, Thomas L., Lawrence, Theodore S., Rehemtulla, Alnawaz, Mikkelsen, Tom, Holland, Eric C., Galbán, Craig J., Ross, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334987/
https://ncbi.nlm.nih.gov/pubmed/22536446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035857
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