DW-MRI as a Predictive Biomarker of Radiosensitization of GBM through Targeted Inhibition of Checkpoint Kinases

PURPOSE: The inherent treatment resistance of glioblastoma (GBM) can involve multiple mechanisms including checkpoint kinase (Chk1/2)-mediated increased DNA repair capability, which can attenuate the effects of genotoxic chemotherapies and radiation. The goal of this study was to evaluate diffusion-...

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Main Authors: Williams, Terence M, Galbán, Stefanie, Li, Fei, Heist, Kevin A, Galbán, Craig J, Lawrence, Theodore S, Holland, Eric C, Thomae, Tami L, Chenevert, Thomas L, Rehemtulla, Alnawaz, Ross, Brian D
格式: Artigo
語言:Inglês
出版: Neoplasia Press Inc. 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610547/
https://ncbi.nlm.nih.gov/pubmed/23544166
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