Population pharmacodynamic model of bicarbonate response to acetazolamide in mechanically ventilated chronic obstructive pulmonary disease patients

INTRODUCTION: Acetazolamide is commonly given to chronic obstructive pulmonary disease (COPD) patients with metabolic alkalosis. Little is known of the pharmacodynamics of acetazolamide in the critically ill. We undertook the pharmacodynamic modeling of bicarbonate response to acetazolamide in COPD...

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Bibliographic Details
Main Authors: Heming, Nicholas, Faisy, Christophe, Urien, Saïk
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334757/
https://ncbi.nlm.nih.gov/pubmed/21917139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10448
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