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Population pharmacodynamic model of bicarbonate response to acetazolamide in mechanically ventilated chronic obstructive pulmonary disease patients

INTRODUCTION: Acetazolamide is commonly given to chronic obstructive pulmonary disease (COPD) patients with metabolic alkalosis. Little is known of the pharmacodynamics of acetazolamide in the critically ill. We undertook the pharmacodynamic modeling of bicarbonate response to acetazolamide in COPD...

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Detalhes bibliográficos
Main Authors: Heming, Nicholas, Faisy, Christophe, Urien, Saïk
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334757/
https://ncbi.nlm.nih.gov/pubmed/21917139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10448
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