Population pharmacodynamic model of bicarbonate response to acetazolamide in mechanically ventilated chronic obstructive pulmonary disease patients

INTRODUCTION: Acetazolamide is commonly given to chronic obstructive pulmonary disease (COPD) patients with metabolic alkalosis. Little is known of the pharmacodynamics of acetazolamide in the critically ill. We undertook the pharmacodynamic modeling of bicarbonate response to acetazolamide in COPD...

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Hlavní autoři: Heming, Nicholas, Faisy, Christophe, Urien, Saïk
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334757/
https://ncbi.nlm.nih.gov/pubmed/21917139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10448
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