Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-blind placebo-controlled randomized withdrawal study

ABSTRACT: INTRODUCTION: To assess the effect of canakinumab, a fully human anti-interleukin-1β antibody, on symptoms and health-related quality of life (HRQoL) in patients with cryopyrin-associated periodic syndrome (CAPS). METHODS: In this 48-week, phase 3 study, patients with CAPS received canakin...

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Bibliografske podrobnosti
Main Authors: Koné-Paut, Isabelle, Lachmann, Helen J, Kuemmerle-Deschner, Jasmin B, Hachulla, Eric, Leslie, Kieron S, Mouy, Richard, Ferreira, Alberto, Lheritier, Karine, Patel, Neha, Preiss, Ralph, Hawkins, Philip N
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334655/
https://ncbi.nlm.nih.gov/pubmed/22152723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3535
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