Rapid and Sustained Long‐Term Efficacy and Safety of Canakinumab in Patients With Cryopyrin‐Associated Periodic Syndrome Ages Five Years and Younger

OBJECTIVE: To assess long‐term efficacy and safety of canakinumab and the response to vaccination in children ages ≤5 years with cryopyrin‐associated periodic syndrome (CAPS). METHODS: CAPS patients (ages ≤5 years) received 2 mg/kg canakinumab subcutaneously every 8 weeks; patients with neonatal‐ons...

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Udgivet i:Arthritis Rheumatol
Main Authors: Brogan, Paul A., Hofer, Michael, Kuemmerle‐Deschner, Jasmin B., Koné‐Paut, Isabelle, Roesler, Joachim, Kallinich, Tilmann, Horneff, Gerd, Calvo Penadés, Inmaculada, Sevilla‐Perez, Belén, Goffin, Laurence, Lauwerys, Bernard R., Lachmann, Helen J., Uziel, Yosef, Wei, Xiaoling, Laxer, Ronald M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Pediatric Rheumatology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899890/
https://ncbi.nlm.nih.gov/pubmed/31161734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41004
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