IL-1 blockade in inherited fever syndromes - what have we learnt?

Por Lachmann, Helen J
Publicado em 2011

Autoinflammatory syndromes as causes of fever of unknown origin

Por Lachmann, Helen J
Publicado no Clin Med (Lond) (2015)

Developments in the scientific and clinical understanding of autoinflammatory disorders

Por Lachmann, Helen J, Hawkins, Philip N
Publicado em 2009

Abnormal N-terminal fragment of brain natriuretic peptide in patients with light chain amyloidosis without cardiac involvement at presentation is a risk factor for development of c...

Por Wechalekar, Ashutosh D., Gillmore, Julian D., Wassef, Nancy, Lachmann, Helen J., Whelan, Carol, Hawkins, Philip N.
Publicado em 2011

Two types of amyloid in a single heart

Por Mahmood, Shameem, Gilbertson, Janet A., Rendell, Nigel, Whelan, Carol J., Lachmann, Helen J., Wechalekar, Ashutosh D., Hawkins, Philip N., Gillmore, Julian D.
Publicado no Blood (2014)

Canakinumab treatment for patients with active recurrent or chronic TNF receptor-associated periodic syndrome (TRAPS): an open-label, phase II study

Por Gattorno, Marco, Obici, Laura, Cattalini, Marco, Tormey, Vincent, Abrams, Ken, Davis, Nicole, Speziale, Antonio, Bhansali, Suraj G, Martini, Alberto, Lachmann, Helen J
Publicado no Ann Rheum Dis (2017)

Diagnosis, Pathogenesis, Treatment, and Prognosis of Hereditary Fibrinogen Aα-Chain Amyloidosis

Por Gillmore, Julian D., Lachmann, Helen J., Rowczenio, Dorota, Gilbertson, Janet A., Zeng, Cai-Hong, Liu, Zhi-Hong, Li, Lei-Shi, Wechalekar, Ashutosh, Hawkins, Philip N.
Publicado em 2009

Whole-Exome Sequencing Revealing Somatic NLRP3 Mosaicism in a Patient With Chronic Infantile Neurologic, Cutaneous, Articular Syndrome

Por Omoyinmi, Ebun, Melo Gomes, Sónia, Standing, Ariane, Rowczenio, Dorota M, Eleftheriou, Despina, Klein, Nigel, Aróstegui, Juan I, Lachmann, Helen J, Hawkins, Philip N, Brogan, Paul A
Publicado em 2014

In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes

Por Lachmann, Helen J., Lowe, Philip, Felix, Sandra Daniela, Rordorf, Christiane, Leslie, Kieron, Madhoo, Sheril, Wittkowski, Helmut, Bek, Stephan, Hartmann, Nicole, Bosset, Sophie, Hawkins, Philip N., Jung, Thomas
Publicado em 2009

Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-bl...

Por Koné-Paut, Isabelle, Lachmann, Helen J, Kuemmerle-Deschner, Jasmin B, Hachulla, Eric, Leslie, Kieron S, Mouy, Richard, Ferreira, Alberto, Lheritier, Karine, Patel, Neha, Preiss, Ralph, Hawkins, Philip N
Publicado em 2011

Clinical characteristics in subjects with NLRP3 V198M diagnosed at a single UK center and a review of the literature

Por Rowczenio, Dorota M, Trojer, Hadija, Russell, Tonia, Baginska, Anna, Lane, Thirusha, Stewart, Nicola M, Gillmore, Julian D, Hawkins, Philip N, Woo, Patricia, Mikoluc, Bozena, Lachmann, Helen J
Publicado em 2013

Clinical profile and treatment outcome of older (>75 years) patients with systemic AL amyloidosis

Por Sachchithanantham, Sajitha, Offer, Mark, Venner, Christopher, Mahmood, Shameem A., Foard, Darren, Rannigan, Lisa, Lane, Thirusha, Gillmore, Julian D., Lachmann, Helen J., Hawkins, Philip N., Wechalekar, Ashutosh D.
Publicado no Haematologica (2015)

Patterns of late gadolinium enhancement in 94 patients with AL or transthyretin cardiac amyloidosis

Por Dungu, Jason, Whelan, Carol J, Gibbs, Simon D, Pinney, Jennifer H, Banypersad, Sanjay M, Venner, Christopher P, Lachmann, Helen J, Wechalekar, Ashutosh, Gillmore, Julian D, Hawkins, Philip N, Anderson, Lisa
Publicado em 2012

Validation of the Auto-Inflammatory Diseases Activity Index (AIDAI) for hereditary recurrent fever syndromes

Por Piram, Maryam, Koné-Paut, Isabelle, Lachmann, Helen J, Frenkel, Joost, Ozen, Seza, Kuemmerle-Deschner, Jasmin, Stojanov, Silvia, Simon, Anna, Finetti, Martina, Sormani, Maria Pia, Martini, Alberto, Gattorno, Marco, Ruperto, Nicolino
Publicado no Ann Rheum Dis (2014)

Natural history and outcome of light chain deposition disease

Por Sayed, Rabya H., Wechalekar, Ashutosh D., Gilbertson, Janet A., Bass, Paul, Mahmood, Shameem, Sachchithanantham, Sajitha, Fontana, Marianna, Patel, Ketna, Whelan, Carol J., Lachmann, Helen J., Hawkins, Philip N., Gillmore, Julian D.
Publicado no Blood (2015)

A prospective study of nutritional status in immunoglobulin light chain amyloidosis

Por Sattianayagam, Prayman T., Lane, Thirusha, Fox, Zoe, Petrie, Aviva, Gibbs, Simon D.J., Pinney, Jennifer H., Risom, Signe S., Rowczenio, Dorota M., Wechalekar, Ashutosh D., Lachmann, Helen J., Gilbertson, Janet A., Hawkins, Philip N., Gillmore, Julian D.
Publicado em 2013

Amyloidogenicity and Clinical Phenotype Associated with Five Novel Mutations in Apolipoprotein A-I

Por Rowczenio, Dorota, Dogan, Ahmet, Theis, Jason D., Vrana, Julie A., Lachmann, Helen J., Wechalekar, Ashutosh D., Gilbertson, Janet A., Hunt, Toby, Gibbs, Simon D.J., Sattianayagam, Prayman T., Pinney, Jenny H., Hawkins, Philip N., Gillmore, Julian D.
Publicado em 2011

Stringent patient selection improves outcomes in systemic light-chain amyloidosis after autologous stem cell transplantation in the upfront and relapsed setting

Por Venner, Christopher P., Gillmore, Julian D., Sachchithanantham, Sajitha, Mahmood, Shameem, Lane, Thirusha, Foard, Darren, Roussel, Murielle, Rannigan, Lisa, Gibbs, Simon DJ, Pinney, Jennifer H, Whelan, Carol J., Lachmann, Helen J., Hawkins, Philip N., Wechalekar, Ashutosh D.
Publicado no Haematologica (2014)

Systemic Amyloidosis in England: an epidemiological study

Por Pinney, Jennifer H, Smith, Colette J, Taube, Jessi B, Lachmann, Helen J, Venner, Christopher P, Gibbs, Simon D J, Dungu, Jason, Banypersad, Sanjay M, Wechalekar, Ashutosh D, Whelan, Carol J, Hawkins, Philip N, Gillmore, Julian D
Publicado no Br J Haematol (2013)

T1 mapping and survival in systemic light-chain amyloidosis

Por Banypersad, Sanjay M., Fontana, Marianna, Maestrini, Viviana, Sado, Daniel M., Captur, Gabriella, Petrie, Aviva, Piechnik, Stefan K., Whelan, Carol J., Herrey, Anna S., Gillmore, Julian D., Lachmann, Helen J., Wechalekar, Ashutosh D., Hawkins, Philip N., Moon, James C.
Publicado no Eur Heart J (2015)