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Reactivity profiles of broadly neutralizing anti-HIV-1 antibodies are distinct from those of pathogenic autoantibodies

OBJECTIVE: Broadly neutralizing antibodies (bNt Abs) against HIV-1 are rarely produced during natural infection, and efforts to induce such Abs by vaccination have been unsuccessful. Thus, elucidating the nature and cellular origins of bNt Abs is a high priority for vaccine research. As the bNt mono...

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Detalhes bibliográficos
Main Authors: Singh, Harvir, Henry, Kevin A., Wu, Sampson S.T., Chruscinski, Andrzej, Utz, Paul J., Scott, Jamie K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334283/
https://ncbi.nlm.nih.gov/pubmed/21508803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32834785cf
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